The Brotman Facial Pain Clinic serves as a venue for several clinical research studies on TMD and related disorders.  The largest and longest research study conducted here is the OPPERA study (Orofacial Pain: Prospective Evaluation and Risk Assessment).  The OPPERA study is a multi-center study aimed at identifying the factors that contribute to the development and persistence of Temporomandibular Disorders (TMD).  In collaboration with Dental Schools at the University of North Carolina – Chapel Hill, University of Florida, and University at Buffalo, the Brotman Clinic served as a recruitment and assessment site for the largest prospective study of TMD funded by the National Institute for Dental and Craniofacial Research.  As of the end of 2017, 32 peer-reviewed papers have been published based on this research.  Other clinical research studies, including those evaluating neural mechanisms underlying normal and pathological pain, have been conducted over the last two decades.

To learn more about currently ongoing studies, visit Clinical Research Currently Recruiting.